01 · Evidence context
What the rating actually records
Fulton defined grades 2-3 as borderline and grades 4-5 as uniformly reproducible positives in that assay. The paper also reports different fatty-acid results when the solvent changed, limiting simple human predictions.
The number is retained as a historical observation. The site does not convert it into a current clinical probability or a complete-product grade.
02 · Formulation context
Why the complete formula can differ
Myristic acid is distinct from esters such as isopropyl myristate and myristyl myristate, which have their own table entries. Exact-name matching prevents the checker from assigning one compound’s score to another.
03 · Practical takeaway
How to use this result proportionately
A rating of 3 is not a product verdict. Compare repeat exposures, formula type, and your own response, and involve a qualified clinician when acne is persistent or treatment decisions are involved.
If you compare products, change one routine variable at a time and use the label from the product currently in hand.
04 · Primary source
Comedogenicity and irritancy of commonly used ingredients in skin care products
Journal of the Society of Cosmetic Chemists, 40, 321-333 · Primary rabbit-ear screening study
Ingredients were generally tested at 10% in a rabbit-ear model. The paper calls the assay extremely sensitive, reports source and vehicle effects, and says the survey is not definitive or a substitute for finished-formula and human evidence.
Open source record ↗